Vyvanse for Adult ADHD – Quick Results

Scientific Study Reveals:
Vyvanse® eases symptoms of Adult ADD/ADHD in as little as one week

In one of the largest controlled stimulant trials of adults with ADD/ADHD, Vyvanse® proved to be significantly more effective than a placebo at managing the symptoms of the disorder. And it did so for some in as short a time as one week.

Those are the results of the Phase II trial of Vyvanse, which the U.S. Food and Drug Administration approved last April for adult use. The drug had already been approved for use in children ages six to 12 years old in July 2007.

Vyvanse® passed not one, but two, standard medical markers of effectiveness. Using a randomized, double-blind, placebo-controlled, parallel-group study which lasted four weeks, the trial involved 414 adults between the ages of 18 to 55. The test also used all the possible dosage levels of Vyvanse ®– 30, 50 and 70 mg.

At each one of these levels the prescription medication, manufactured by Shire Corp. outperformed the placebo.

Researchers used the ADHD Rating Scale which contains 18 separate diagnostic criteria as outlined by the Diagnostic and Statistical Manual of Mental Disorders, the official publication of the American Psychiatric Association. This scale is a validated method for assessing ADD/ADHD symptoms. Using this scale symptoms were reduced by up to 45 percent.

The scientists also used another measurement marker, the Clinical Global Impressions-Improvement scale as well. The percentage of adults who experienced a reduction of symptoms using Vyvanse who said they were “much improved” or “very much improved” according to investigators, ranged from 57 to 61 percent by the end of the study.

If you would like to view the entire article regarding this trial, you can click here.

Dr. Kenny

[tags] vyvanse, ADHD Medication, Adult ADHD, Adult ADD [/tags]


  1. One week? My 3 children (now grown) showed very obvious improvement almost 30 years ago with just 5 mg. ritalin the first morning they took it–and this was not at home, but in kindergarten class!

  2. Is there a risk of taking Vyvanse when you get too old? I take it now (36 y.o)I have a ways to go yet, but just curious. Some meds like Abilify say for the elderly not to take. Thanks, ad3

  3. I have been taking Vyvanse for 2 1/2 years and it is like a miracle drug. My insurance company pulled it from their formulary 1 year ago and only pays $30 out of $190 a month perscription cost. Any help out there for people with insurance that pays nearly nothing? I have appealed and gotten nowhere.

  4. I have a question for Dr. Kenny…
    I have been taking adderall IR, not XR for a few years now and have built up a tolerance for it. In search of a new drug that can help, my psychiatrist prescribed Vyvanse. He started me at 30mg, and it made me feel so completely out of it, I am reluctant to take it again. I’ve been taking 20mg adderall’s 3x a day since it doesn’t last me very long.

    Is 30mg too small a dosage for the vyvanse? Is that why it’s making me feel like this, or should I tough it out and give it a week or so? I could also split open a capsule and take have of that in addition to the 30….

    Any suggestions would be very helpful!

    • Brigit – you’ll need to talk to your doctor.
      It is unclear if you are ‘out of it’ because you are significantly under medicated (i.e. Vyvanse 30 mg is like taking adderall IR 10 mg in the day – which is much less than your current 60 mg per day), or you may be having side effects to Vyvanse.
      Talk to your doctor about this.
      Good luck.
      Dr. Kenny

  5. Dr. hanndalmani got diagnosed at 7 yrs old for adhd,but folks did not want to try meds so just therapy.which of course did not help at all.finally when i was 15 my teachers saw i was acting out not doing work and i finally got put on ritilin,but it was to late for school i hit 16 dropped out,but on meds things changed i made friends,worked,could finish a task,depression and anxiety was getting better.anyway we ended up moving and my new doc put me on adderall,worked even better than ritilin,i went and got g.e.d.,started technical school,haad good job girls,and my family finally stopped thinking i was weird.Anyway i was so happy,then i fell and broke my back,So my back doc had me on oxycontin 80mg for 2 yrs,my other doclowered my dose of adderall from 2 20mg a day to 2 10 mg,because of the mixture,i still was descent.and then one night i had a seizure and everybody from my mom to doc at hospital accused me of o.d.ing.anyway my fam doc completely cut me off adderall, itried to talk to him but nothing.so that pretty much ended me 11 years of hell,my backk got better but i needed opiates now to take care of symptoms of adhd. i tried antidepressants anything u can think of.So i totally blame that doc for messing up these last 11yrs.i needed p meds for a while but not 11 yrs.so anyway i could not work,would not leave house.itried 2 times to get back on adderall but could not pay.but when i did i saw differences.anyway i finally got my life back.bbeen off bad opiates for2/1/2 yr,but i am on suboxone but im down to 4mg.and i am also on 50mg vyvanse.And i got my life back,i still cant work,but i have started my on addiction group,i go on dates,dont avoid family,depression is gone,and anxiety,i saw my 4 yr old daughter only for second time and she is 4.i really feel that dr screwed my life up,and i was strung out for 11 yrs,igot off oxys after 2 yrs but was put onprecocett i use to take 25 a day,10 first thing in morning.anyway i wanted to get your thoughts about an addict being on vyvanse. i never hear from you please write me back. James T

  6. i am currently taking vyvanse 30mg… started a week ago and at first thought it wasn’t for me… i seem to have adjusted. but i’m wondering about dosage… i was taking 30 to 40 mg of dexedrine before in 10mg doses, 3 or 4 times a day as needed. so how does a 30mg slow release vyvanse compare to that? is it enough?

  7. At 51, I’ve been taking Vyvanse now for well over a year, and am thrilled to say, I’ve experienced almost miraculous results in managing my life. Seriously, like night and day.
    Problem is, I’ve been at 70 mg now for the last 8 months, and have become acutely aware that even 70 mg can become virtually ineffective over time. My doctor and I have discussed this frustration on several occasions, but outside of introducing a supplemental ADD med to add in combination with Vyvanse, there’s very little else that can be done. Which ordinarily wouldn’t be a concern if I had insurance to cover the additional cost. Which I don’t.
    So now what?
    I mean, given the general ineffectiveness of Vyvanse for me at this point, continuing on seems to be quite honestly a waste of money. Yet reverting back to a complete ‘schlub’ after making such monumentally encouraging strides is a little disheartening.
    Any thoughts?

  8. I have been an opiate addict for 11 years,i was diagnosed with adhd at age 9 but did not get the right treatment,so i tried self medicating with pot nothing big,then i broke my back and found what i thought i needed.anyway my life went down hill after a while i took it just to feel normal.after arrest,failed marriage,and about 6 rehabs i still could not get off them.finally i found suboxone,and man it was a miracle drug,started on 32mg a day,it was working but something was missing.so i decided to go to a phsychiatrist and try treatment for adhd.anyway he put me on 50mg vyvanse,within a week i was doing great,i even did not need that high a dose of suboxone.now im only on 8mg of suboxone,and slowly coming off.he did put me on 70 mg vyvanse,but the point is i was using opiates to deal with adhd.now that my brain is working betteri dont feel i will ever get back on opiates,as long as i take the vyvanse.oh and i dont abuse the vyvanse either,cause one a day makes me stable.anyway those are two excellent medications.they saved my life.

  9. Vyvanse worked for me immediately. I love it. slowed me right down and I always know where my keys are. I am not hungry so I have to make sure to eat and I could easily stay up and busy til 3 am but if I go to bed at 10, I fall right to sleep.. BUT my blood pressure is extremely high and my eyes got real bad this past year. I am afraid

  10. I was replying to others comments about needing more medication for the effect. I have found that what parents do for children who are in school, going on drug holidays has worked for me, just because i’m a returning adult student, and getting on a medication that works for me has been difficult. I felt like Adderal was a miracle drug for me as well about a year ago. During my breaks from school i would go off my adderall for about 2 weeks, and after that 2 weeks my tolerance would decrease. I have to say over the past year because i have done this (drug holiday) i have not built up much tolerance. I recently went off adderall because my Dr. quit on me (me forgetting appt after appt i guess). Anyways, i joined a study (to afford the meds) and found a local hospital that has different adult studies going on where i could get the meds at no cost and actually get paid to take my meds! Anyways, i am on Ritilin LA (long acting) and its great! its better than the Adderall. Just wanted to share all this cause sometimes it seems one med is the only one working, but there are other ones that some Dr.s wont prescribe off label, cause its only out there for children right now, but i know how it feels to be on a medication and not know wha tyou had missed before, though you knew your life was a mess. So there are some options for us adults, since there are quite enough clinical trials for meds out there to get the same meds approved for children approved for us adults as well (as far as not being able to pay for the meds and trying someting else in the same classification of medication).

  11. Oh yeh, and by the way i tried vyvance, and it worked awful for me! So, what works for one may not work for another, and this is how these meds get approved for adult use is when us adults can do these trials (for meds your dr. may already be prescribing for you)> I found a trial for the Focalin XR and was paying for that myself out of pocket (at least 175 a month) about 5 years ago, its its still not approved. I was surprised i was getting it still prescribed, so anyways, those who mentioned cost here, wanted ya to know there are options.

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